Believe it or not, our bodies naturally contain many active fungi chemicals just like Amanita Muscaria. Similar to medicines that come from botanicals, many of the chemicals that fungi produce to flourish in the wild are also active in humans. This is likely not a coincidence. It is an evolutionary advantage for humans to coevolve with our environment and our medicines.
That’s what makes this mushroom micro-dosing safe for humans, while the mycelium - one of the chemicals in Amanita - keeps hundreds of millions of hungry microbes and predators at bay. Mushrooms did not evolve to become medicine for humans but rather evolved to survive their own predators. In fact, it is likely the mushroom's relationship with microbes that make them medicinal for humans.